Refine, Redefine
Refine Biology, Redefining Nature
Powered by Plant Extraction and Synthetic Biology
A trusted innovation partner for the global health industry.
Natural. Effective. Sustainable.
Founded in 2007, Refine Biology strives to provide purer natural ingredients, high-efficiency solutions and eco-friendly innovation.
Driven by rigorous science and continuous exploration, we partner closely with customers to grasp their unique requirements. Breaking the boundaries of existing frameworks, we harness synthetic biology to create new opportunities for natural ingredients.
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Driven by Innovation,
Tailored for You
Innovation-led, customer-focused. We supply premium natural ingredients and tailored solutions to accelerate your product development and business growth.
Natural Sweetener Platform
We provide erythritol, allulose, steviol glycosides, sweetness enhancers and customized sweetener blends for sugar-free and reduced-sugar food and beverage applications.
Learn More →Functional Ingredients Platform
We develop functional ingredients for use in energy, weight management, healthy aging, beauty-from-within and general wellness formulations.
Learn More →Natural Flavor Platform
We carefully select premium botanicals, fruits and herbs to deliver authentic, well-balanced natural flavors and customized solutions for food and beverage applications.
Learn More →Animal Nutrition
Focusing on natural alternatives to antibiotics and sustainable protein solutions, we support safer and more sustainable animal nutrition.
Learn More →Full-Process Empowerment
Built upon six core technology platforms, we merge AI and synthetic biology to unlock innovation for natural product development.
We uphold every promise of nature to build global trust.
AI-Driven Technology R&D Platform
Our integrated technology platforms boost product quality, process efficiency and supply reliability while lowering environmental footprint. We strive to drive sustainable development of natural ingredients and support the shift toward a low-carbon future.
- Prokaryotic Microorganism Gene Editing Platform
- Eukaryotic Microorganism Gene Editing Platform
- High-Throughput Strain Screening & Directed Evolution Platform
- Enzyme Engineering Platform
- Fermentation Engineering Platform
- Separation Engineering Platform
From Biofoundry Innovation
to Industrial Production
Our three smart manufacturing sites in China bridge lab-scale biofoundry innovation and industrial production. Leveraging our proprietary Design-Build-Test-Learn workflow, we seamlessly translate engineered strain designs into commercial-scale fermentation.
News & Insights
Explore the latest updates, industry insights, and exhibition news from Refine.



Empowering Global Partners
Making every natural promise a solid foundation for earning global trust.
We uphold every promise of nature to build global trust.




































