Engineering Cell Factories
Refine Biology leverages six synthetic biology engineering platforms—from gene editing and directed evolution to fermentation and purification—to build high-performance microbial cell factories. Our vertically integrated technology system accelerates the development and industrial-scale production of natural functional ingredients.
Separation Engineering Platform
Separation Engineering Platform
Our platform focuses on the complete downstream separation and purification workflow for fermentation broths. We possess a full suite of core separation capabilities including high-pressure homogenization for cell disruption, membrane separation (microfiltration/ultrafiltration/nanofiltration), continuous ion-exchange chromatography, preparative chromatography, simulated moving bed (SMB), and industrial crystallization.
Full Suite of Core Separation Capabilities
Covering membrane separation, continuous ion-exchange chromatography, and industrial crystallization
Precision Preparative & Chromatographic Separation
Efficient purification via simulated moving bed (SMB) and preparative chromatography
Flexible Multi-Unit Combination
Customized low-energy purification processes for intracellular and extracellular products
High-Yield Scale-Up Process
Breaking purity bottlenecks with easily scalable high-recovery workflows